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Chlorine dioxide (CD) gas sterilization is an alternative to ethylene oxide and other sterilization modalities and is of high interest to the EPA and FDA due to its sustainability and effectiveness. The dry method of generating CD gas generates a greater than 99% pure form of CD gas, an oxidizer that is non-carcinogenic and non-explosive at use concentrations and can perform sterilization at ambient temperature.
The benefits of CD are that cycle times average only 4 to 6 hours, helping shorten the supply chain; it lacks harmful residues and breaks down only into benign ions; monitoring and controlling parameters within the cycle is highly robust. CD gas also has a yellow-green color, allowing for a UV-vis spectrophotometer to accurately read concentration throughout the cycle and provide close monitoring. This allows for the opportunity to utilize parametric release during cycles.
This webinar by ClorDiSyS Solutions details how CD gas sterilization works, validation strategies, key regulatory considerations and real-world application examples.
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