
Global innovation platform Plug and Play announced the selection of its fifth Medtech cohort. This batch of startups will join the accelerator program in Warsaw, Indiana, to drive the next generation of healthcare and medical device solutions.
Over the next several months, the entrepreneurs will collaborate closely with Plug and Play Medtech corporate partners, including Parkview Health and Zimmer Biomet, to refine their technologies, explore opportunities, and scale their impact within the healthcare ecosystem.
The Batch 5 program focuses on high-impact areas, including AI workflow automation, remote patient monitoring, and advanced orthopedic solutions. Working alongside the program’s corporate partners provides startups with a unique vantage point:
- Zimmer Biomet: Startups will engage to explore advancements in surgical robotics, data-driven implants, and digital health.
- Parkview Health: Founders will gain insights into clinical workflows and patient experience, ensuring their solutions address the practical needs of modern health systems through the Mirro Center for Research and Innovation.
The selected startups represent a diverse range of technologies. Those with orthopedic applications include:
- Amplicore Pharma: Amplicore delivers next‑generation regenerative therapies that target the root causes of musculoskeletal degeneration.
- Cohesys: Cohesys has developed BoneTape, the first resorbable, drill-free bone fixation system enabling rapid, reversible fixation without screws or bone preparation.
- Dencoda: Dencoda’s DNA-based protein activity assay delivers early, accurate osteoarthritis detection and accelerates arthritis drug
development - Eclipse Orthopaedics: Integrated imaging and drilling to guide complex trauma surgeries
- JWP GmbH Drug Eluting Solutions: JWP is developing drug-eluting bone grafts that act as local therapeutic systems, enabling sustained infection control while supporting bone regeneration.
- OrthoSens: Transforming standard implants into connected, recurring revenue engines
- OsteoCure Therapeutics: OsteoCure develops surgeon-delivered, local therapies that accelerate fracture healing and fusion, reduce post-operative pain, enhance implant osteointegration, and help prevent infection, improving outcomes while minimizing systemic exposure.
- Phoenix Kinetics: Phoenix Kinetics is the company rededicated to the success of a critical advancement in the preservation of motion and the biomechanical movement of forces through the knee. The NUsurface Medial Meniscus Replacement addresses the current unmet clinical need for those with early knee osteoarthritis who are too old for meniscal allograft transplantation—yet are too young for, or are unwilling to have, total knee arthroplasty.
- Rebio Health: Rebio Health develops electrochemical sterilization that targets biofilm infections on orthopedic implants, enabling safer, less invasive treatment and reducing implant-removal surgeries.
- Sceptre Surgical: Sceptre Surgical is a surgeon-led medtech company developing a patent-pending single-use sonic brush that breaks up biofilm on orthopedic implants, providing surgeons with a simple and effective tool to help save the lives and limbs of patients with implant infections.
The program will culminate in the Warsaw Medtech Expo on September 2, where the cohort will pitch their progress to an audience of venture capitalists, corporate executives, and healthcare leaders.
Source: Plug and Play
JAV
Julie A. Vetalice is ORTHOWORLD's Editorial Assistant. She has covered the orthopedic industry for over 20 years, having joined the company in 1999.



